Keppetipola
Research
Group
Role of Chemical Modifications in RNA Binding Protein and mRNA Processing
Our lab is interested in understanding how chemical modifications in RNA binding proteins play a role in regulating alternative splicing of premature messenger RNA transcripts and in turn, tissue specific gene expression patterns. We use the polypyrimidine tract binding protein family as a model system to carry out our studies. Two main research areas in the lab are to 1) understand the role of phosphate modifications and 2) the role of acetyl modifications in RNA binding protein function. We use a combination of molecular biology, biochemistry and cell biology techniques to carry out our studies.
Fall 2024 News:
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Kennedie Doyle (from Fullerton College) is doing an internship in the lab this fall. Welcome!
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Sammy's abstract was accepted for SACNAS! She will be presenting and attending the conference with the CSUF NAARE program.
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Issac, Sammy, and Maddie's abstracts were accepted for SCCUR. Congratulations guys!
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Freshman Manasvi Chavan and Johnny Ramos are interested in our research and will be joining us every Friday during research group meetings this fall. We're happy you're interested in our work!