# CSUF graduate student     *CSUF undergraduate student coauthor

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• Truong, A*., Barton, M*., Tran, U., Mellody, M#., Berger, D., Madory, D., Hitch, E., Jibrael, B., Nikolaidis, N., Luchko, T., & Keppetipola, N. (2024). "Unstructured linker regions play a role in the differential splicing activities of paralogous RNA binding proteins PTBP1 and PTBP2". The Journal of Biological Chemistry, 300(3), 105733–105733. doi: 10.1016/j.jbc.2024.105733

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• Pina, J. M#., Hernandez, L. A., & Keppetipola, N. M. (2022). Polypyrimidine tract binding proteins PTBP1 and PTBP2 interact with distinct proteins under splicing conditions. PloS one, 17(2), e0263287. 

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• Niroshika Keppetipola and Terri Patchen (2021) “Titrating Teaching: An Interdisciplinary Case Study of Online and Face-to-Face Undergraduate Biochemistry Instruction” J Microbiol Biol Edu doi: 10.1128/jmbe.v22i1.2603.

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• Camila Pimentel, Casin Le , Marisel R Tuttobene, Tomas Subils , Jasmine Martinez , Rodrigo Sieira ,Krisztina M Papp-Wallace, Niroshika Keppetipola, Robert A Bonomo, Luis A Actis , Marcelo E Tolmasky , Maria Soledad Ramirez  (2021) “Human Pleural Fluid and Human Serum Albumin Modulate the Behavior of a Hypervirulent and Multidrug-Resistant (MDR) Acinetobacter baumannii Representative Strain” Pathogens Apr 13;10(4):471

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• Ontiveros RJ, Hernandez L, Nguyen H, Hernandez Lopez AL, Shankar A, Kim E, Keppetipola N* (2020) “Identification and Characterization of a Minimal Functional Splicing Regulatory Protein, PTBP1” Biochemistry 2020, 59 (50) 4766–4774

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• Martinez AA#, Espinosa BA*, Adamek RN*, Thomas BA, Chau J*, Gonzalez E*, Keppetipola N, Salzameda NT (2018) “Breathing new life into West Nile virus therapeutics; discovery and study of zafirlukast as an NS2B-NS3 protease inhibitor ” Eur J Med Chem. Aug 31;157:1202-1213

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• Pina J#, Reynaga JM*, Truong A*, and Keppetipola N (2018) “Post-translational modifications in Polypyrimidine Tract Binding Proteins PTBP1 and PTBP2” Biochemistry Jul 3;57(26):3873-388

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• Keppetipola NM, Yeom KH, Hernandez AL, Bui T*, Sharma S, Black DL (2016) “Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2. RNA 22(8):1172-80

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• Keppetipola N, Sharma S, Li Q, and Black DL. (2012) “Neuronal regulation of Pre-mRNA Splicing by Polypyrimidine Tract Binding Proteins, PTBP1 and PTBP2” Crit Rev Biochem Mol Biol. 47(4):360-78.

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• Keppetipola N, Jain R, Meineke B, Diver M, and Shuman S. (2009) “Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease.” RNA 15, 1036-44.

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• Keppetipola N, and Shuman S. (2008) “A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3' cyclic nucleotide phosphodiesterase activity” J. Biol. Chem. 283, 30942-9

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• Keppetipola N, and Shuman S. (2007) “Characterization of the 2’, 3’ cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase” Nucleic Acids Res. 35, 7721-32.

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• Keppetipola N, Nandakumar J, and Shuman S. (2007) “Reprogramming the end healing pathway of a bacterial RNA repair enzyme.”  Nucleic Acids. Res.35, 3624-3630.

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• Keppetipola N, Jain R, and Shuman S. (2007) “Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily” J. Biol. Chem. 282, 11941-9.

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• Keppetipola N, and Shuman S. (2006) “Distinct enzymic functional groups are required for the phosphomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase.” J. Biol. Chem. 281, 19251-19259.

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• Keppetipola N, and Shuman S. (2006) “Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase.” RNA 12, 73-82.

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• Keppetipola N, and Shuman S. (2005) “Characterization of a thermophilic ATP-dependent DNA ligase from the euryarchaeon Pyrococcus horikoshii..” J. Bacteriol. 187, 6902-8.

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